A new method to be implemented within the scope of a TÜBİTAK project conducted at Hitit University aims to detect and halt tissue damage occurring in diabetes.
The project, titled "Investigation of the Effect of Trans-Aconitic Acid on the Liver in a Streptozotocin (STZ)-Induced Type I Diabetes Model," led by Prof. Dr. Menderes Suiçmez, Head of the Department of Molecular Biology and Genetics at the Faculty of Science and Letters, has been awarded funding under the TÜBİTAK 1002 Rapid Support Program.
The project will investigate the therapeutic properties of trans-aconitic acid (TAA), a fatty acid obtained from various plants and seeds, and its effects on halting tissue damage.
The project will involve the application of trans-aconitic acid (TAA), a substance for which there is no prior anti-diabetic study and which is thought to have therapeutic potential, within a diabetes model to be developed.
Prof. Dr. Menderes Suiçmez stated in his açıklama that diabetes, commonly known as sugar disease, is a widespread immune system disease at both national and international levels.
Suiçmez explained that diabetes occurs when insulin produced in the body cannot bind to target cells, emphasizing that diabetes leads to damage in cellular structures and structural changes in proteins.
He said that anti-diabetic drugs and antioxidant defense systems are important in the treatment of diabetes and continued:
“In our project, we will develop a new method and apply trans-aconitic acid (TAA), which has not been previously studied as an anti-diabetic drug and is thought to have therapeutic potential. We expect this method to have a healing effect and repair tissue damage. If our project yields positive results, I believe we will make a significant contribution to the diagnosis and treatment of tissue damage that diabetic patients frequently encounter. Our aim is to benefit people by serving society through the studies we conduct.”
